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| 產(chǎn)品英文名稱 | Rat IL-6 Protein |
| 產(chǎn)品中文名稱 | 重組大鼠白介素-6 |
| 別名 | Interleukin6;IL-6;IL6;IL 6;MGI2-A;MGI2A;HGF;BSF2;HSF;IFNB2;B-Cell Stimulatory Factor-2;Hybridoma/Plasmacytoma Growth Factor;Hepatocyte Stimulating Factor;Cytotoxic T-Cell Differentiation Factor |
| 標簽 | 無標簽 |
| 表達宿主 | 大腸桿菌 |
| 種屬 | 大鼠 |
| 序列 | 氨基酸序列來源于：鼠源IL 6 P20607 (F25-T211) 表達的蛋白片段。 |
| 活性 | Testing in Progress |
| 蛋白長度 | 重組大鼠白細胞介素6 由187個氨基酸組成，預測分子量為21.73 KD。 |
| 純度 | > 99% ，使用SDS-PAGE檢測 |
| 特點&優(yōu)勢 | 通過LAL法測定，每微克蛋白里內(nèi)毒素含量<1.0> |
| 產(chǎn)品形式 | 凍干粉，凍干緩沖液為無菌的20 mM Tris，150 mM NaCl，pH 7.4。 |
| 基因ID | M26744.1 |
| 蛋白序列鏈接 | Il6 - Interleukin-6 - Rattus norvegicus (Rat) | UniProtKB | UniProt |
| 使用中注意事項 | 開蓋使用前，請先離心。本產(chǎn)品為凍干粉，推薦用該產(chǎn)品配套的Reconstitution Buffer 10 mM HCl進行復溶，且濃度不低于100 µg/mL?？蛻艨筛鶕?jù)后續(xù)的實驗需求，進行進一步的稀釋。 |
| 保存建議 | 本產(chǎn)品為凍干粉形式，建議：將凍干粉產(chǎn)品保存于-20℃以下的干燥環(huán)境中。本產(chǎn)品溶解之后，可在4℃保存2-7天，長期使用請置于-20℃以下。為長期保存，推薦添加載體蛋白（0.1% HAS/BSA或10%FBS），并酌情分裝保存，避免反復凍融。 |
| 運輸條件 | 冰袋運輸（藍冰） |
| 警告 | 本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應用，不是建議使用我們的產(chǎn)品去違反任何或許可證。對于使用本產(chǎn)品可能發(fā)生的侵權或其他違規(guī)行為，我們不承擔任何責任。 |
| 背景 | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity. |
Fig.Rat IL-6 Protein
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