細胞名稱

人支氣管上皮細胞16HBE

貨物編碼

BFN608008569

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研           2類

培養(yǎng)體系

DMEM高糖培養(yǎng)基+10%FBS+1%雙抗 

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡介

人支氣管上皮細胞16HBE取自男性供體，經(jīng)過SV40永生化處理，不規(guī)則形態(tài)。

注釋

Characteristics: Widely used to model barrier function of the airway epithelium and to study respiratory ion transport as well as the function of CFTR (Millipore).

Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [pSVori-].

Omics: Array-based CGH.

STR信息

Amelogenin        X

CSF1PO        11

D3S1358        16

D5S818        11,12

D7S820        11

D8S1179        10,11

D13S317        11

D16S539        12,13

D18S51        14

D21S11        28,30.2

FGA        21,22

Penta D        9

Penta E        5,14

TH01        9.3

TPOX        8

vWA        16,18

參考文獻

PubMed=10498856; DOI=10.1038/sj.bjp.0702772

Goncz K.K., Feeney L., Gruenert D.C.

Differential sensitivity of normal and cystic fibrosis airway epithelial cells to epinephrine.

Br. J. Pharmacol. 128:227-233(1999)

PubMed=12711171; DOI=10.1016/S0378-5173(03)00129-7

Forbes B., Shah A., Martin G.P., Lansley A.B.

The human bronchial epithelial cell line 16HBE14o- as a model system of the airways for studying drug transport.

Int. J. Pharmaceut. 257:161-167(2003)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040

Gruenert D.C., Willems M., Cassiman J.J., Frizzell R.A.

Established cell lines used in cystic fibrosis research.

J. Cyst. Fibros. 3:191-196(2004)

PubMed=18441018; DOI=10.1194/jlr.M700388-JLR200

Andersson C., Al-Turkmani M.R., Savaille J.E., Alturkmani R., Katrangi W., Cluette-Brown J.E., Zaman M.M., Laposata M., Freedman S.D.

Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism.

J. Lipid Res. 49:1692-1700(2008)