細(xì)胞名稱

人卵巢癌細(xì)胞IGROV-1

貨物編碼

BFN60805258

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細(xì)胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運(yùn)輸方式

常溫保溫運(yùn)輸

干冰運(yùn)輸

安全等級(jí)

1

用途限制

僅供科研           2類

培養(yǎng)體系

DMEM高糖+10%FBS+1%雙抗

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡(jiǎn)介

人卵巢癌細(xì)胞IGROV-1取自47歲女性供體

注釋

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: COSMIC cell lines project.

Part of: KuDOS 95 cell line panel.

Part of: MD Anderson Cell Lines Project.

Part of: NCI-60 cancer cell line panel.

Part of: OCCP ovarian cancer cell line panel.

Doubling time: 30 hours (PubMed=25984343); ~23 hours (PubMed=10817511); 28 +- 1 hours (PubMed=9636834); 31 hours (NCI-DTP); 19.53 hours 

Microsatellite instability: Instable (MSI-high) (PubMed=31068700; Sanger).

Omics: Array-based CGH.

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: Fluorescence phenotype profiling.

Omics: Genome sequenced.

Omics: lncRNA expression profiling.

Omics: Metabolome analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: shRNA library screening.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Misspelling: IGROV-4; In PubMed=12960427.

Misspelling: IGR-OV1-RU; In Cosmic 1175880.

STR信息

Amelogenin        X

CSF1PO        11,13,14,15 (Cosmic-CLP)

11,13 (PubMed=19372543; PubMed=30485824)

11,16 (PubMed=25230021)

11,13,15 (PubMed=25877200)

D2S1338        17,25

D3S1358        13,15 (PubMed=19372543)

13,14,15 (PubMed=25230021; PubMed=25877200)

D5S818        12,13 (Cosmic-CLP; PubMed=19372543; PubMed=25230021)

12 (PubMed=25877200; PubMed=30485824)

D7S820        11 (Cosmic-CLP)

10 (PubMed=25877200)

9.1,10.1,11.1 (PubMed=25230021)

9.3,10.1 (PubMed=30485824)

D8S1179        14,16

D13S317        8,10

D16S539        11,12 (Cosmic-CLP; PubMed=19372543; PubMed=25877200)

12 (PubMed=25230021)

11,13 (PubMed=30485824)

D18S51        14,16,17 (PubMed=25230021)

15,16 (PubMed=25877200)

D19S433        13,14

D21S11        26,29.2,30.2 (PubMed=25230021)

26,30.2 (PubMed=25877200; PubMed=30485824)

FGA        20,21,26 (PubMed=25230021)

21,26 (PubMed=25877200)

Penta D        8,10

Penta E        13,17

TH01        7,9.3

TPOX        8,11,12 (Cosmic-CLP)

8,11 (PubMed=19372543; PubMed=25230021; PubMed=25877200; PubMed=30485824)

vWA        17,21 (Cosmic-CLP; PubMed=19372543; PubMed=30485824)

16,17,20,22 (PubMed=25230021)

17,21,22 (PubMed=25877200)

參考文獻(xiàn)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005

Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.

Characterization of human cancer cell lines by reverse-phase protein arrays.

Cancer Cell 31:225-239(2017)

PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096

Papp E., Hallberg D., Konecny G.E., Bruhm D.C., Adleff V., Noe M., Kagiampakis I., Palsgrove D., Conklin D., Kinose Y., White J.R., Press M.F., Drapkin R., Easwaran H., Baylin S.B., Slamon D., Velculescu V.E., Scharpf R.B.

Integrated genomic, epigenomic, and expression analyses of ovarian cancer cell lines.

Cell Rep. 25:2617-2633(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747

Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Nature 569:503-508(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023

Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E., Schweppe D.K., Jedrychowski M., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.

Quantitative proteomics of the Cancer Cell Line Encyclopedia.

Cell 180:387-402(2020)