鹽酸依特卡肽 1334237-71-6，KAI-4169

英文名：Etelcalcetide hydrochloride

(6R,9R,12R,15R,18R,21R,24S,29R)-24-Acetamido-1,29-diamino-12,15,18-tris(3-carbamimidamidopropyl)-6-carbamoyl-1-imino-9,21-dimethyl-8,11,14,17,20,23-hexaoxo-26,27-dithia-2,7,10,13,16,19,22-heptaazatriacontan-30-oic acid hydrochloride (1:1)

AMG 416

velcalcetide hydrochloride

etelcalcetide hydrochloride

KAI-4169

UNII:72PT5993DU

AMG-416

中文名：鹽酸依特卡肽

CAS：1334237-71-6

分子式：C38H73N21O10S2.xClH

分子量：1084.712

結(jié)構(gòu)式：

***質(zhì)量：1083.505737

描述：Etelcalcetide hydrochloride (AMG 416 hydrochloride) 是一種合成肽，有鈣敏感受體 (CaSR) 活化劑的作用。Etelcalcetide hydrochloride 可有效降低接受血液透析的繼發(fā)性甲狀旁腺功能亢進患者的甲狀旁腺*** (PTH) 濃度。

參考文獻：

[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.

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鹽酸依特卡肽 1334237-71-6，KAI-4169