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55683-37-9，Propargyl-PEG1-COOH化學特性
閱讀：55 發(fā)布時間：2022-7-8| 提 供 商 | 陜西新研博美生物科技有限公司 | 資料大小 | 25.6KB |
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英文名稱：Propargyl-PEG1-acid
Propargyl-PEG1-COOH
3-Prop-2-ynoxypropanoic acid
分子式：C6H8O3
分子量：128.1
CAS NO: 55683-37-9
MDL number:MFCD10689189
純度:95%
保存方法:-20°C避光，避濕
產品簡介：
Propargyl-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains a single PEG unit to help improve solubility.
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