化工儀器網(wǎng)
資料下載
DSPE-PEG2000-FA, Folate-PEG-DSPE
閱讀：516 發(fā)布時(shí)間：2018-10-25| 提 供 商 | 陜西新研博美生物科技有限公司 | 資料大小 | 5.3KB |
|---|---|---|---|
| 資料圖片 | 下載次數(shù) | 25次 | |
| 資料類(lèi)型 | JPG 圖片 | 瀏覽次數(shù) | 516次 |
| 免費(fèi)下載 | 點(diǎn)擊下載 |
DSPE-PEG2000-FA, Folate-PEG-DSPE
中文名稱(chēng)：二棕櫚酰磷脂酰乙醇胺-聚乙二醇-葉酸
英文：1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethyleneglycol)]
產(chǎn)品外觀：淡黃色粉末
溶解度：>5mg/mL in hot water, chloroform, DMSO
PEG分子量：2000
整體分子量：3200
結(jié)構(gòu)式：
產(chǎn)品純度：90%
產(chǎn)品包裝：50mg
價(jià)格：4250元
保存條件：-20℃
保存時(shí)間：1年
產(chǎn)品用途：用于腫瘤主動(dòng)靶向
供應(yīng)商：陜西新研博美生物科技有限公司
TELE： 請(qǐng)點(diǎn)擊此處進(jìn)入陜西新研博美生物科技有限公司展臺(tái)查看
MOBLE：請(qǐng)點(diǎn)擊此處進(jìn)入陜西新研博美生物科技有限公司展臺(tái)查看
產(chǎn)品描述：
DSPE-PEG-Folate (DSPE-PEG-FOL) conjugate,which can be incorporated into liposomes as a targeting ligand. Folatereceptors are cellular surface markers for numerous solid tumors and myeloidleukemias.
Folate targeted drug delivery has emergedas an alternative therapy for the treatment and imaging of many cancers andinflammatory diseases. Due to its small molecular size and high bindingaffinity for cell surface folate receptors (FR), folate conjugates have theability to deliver a variety of molecular plexes to pathologic cells withoutcausing harm to normal tissues. Complexes that have been successfully deliveredto FR expressing cells, to date, include protein toxins, immune stimulants,chemotherapeutic agents, liposomes, nanoparticles, and imaging agents. Thisreview will summarize the applications of folic acid as a targeting ligand andhighlight the various methods being developed for delivery of therapeutic andimaging agents to FR-expressing cells.