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Bim (phospho Ser59) rabbit pAb
  • Bim (phospho Ser59) rabbit pAb

更新时间:2025-06-28 16:04:52

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SourceRabbitApplicationsIHC,ELISAReactivityHuman,Mouse,RatDilutionIHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Bim (S59) Polyclonal Antibody detects endogenous levels of Bim protein only when phosphorylated at S59.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human BIM around the phosphorylation site of Ser59. AA range:31-80

  • Uniprot No

    O43521

  • Alternative names

    BCL2L11; BIM; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    BCL2 like 11(BCL2L11) Homo sapiens The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013],

  • Other

    BCL2L11, Bcl-2-like protein 11

  • Mol.Wt (Da)

    22171

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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