Caldesmon钙结合蛋白（兔单克隆抗体）

广州健仑生物科技有限公司

钙调蛋白是细胞第二信使系统的重要成分，在Ca信号系统传导中起着关键的作用，调控生理代谢及基因表达，控制细胞正常的生长和发育。钙调蛋白作为第二信使在植物信号转导中的作用一直是植物生理、细胞生物学和发育生物学研究的热点。Ca/CaM是有机体进化过程中zui保守的信号转导级联反应系统，这一信号途径广泛存在于真核细胞中，并在各种细胞活动如胁迫反应和细胞增殖中起调节作用。这种Ca/CaM信号系统存在的普遍性和保守性·对钙调蛋白的研究可以使我们可以更好地利用其功能为人类服务。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

欢迎咨询

欢迎咨询

【产品介绍】

细胞定位：细胞浆

适用组织：石蜡/冰冻

阳性对照：甲状腺髓样癌

抗原修复：热修复（EDTA）

抗体孵育时间：30-60min

Caldesmon钙结合蛋白（兔单克隆抗体）

诊断检查
白细胞计数及分类；反复做真菌直接涂片和培养。支气管刷液或支气管肺泡洗液可提高阳性率。血液分离曲菌很少阳性。尿、便、腹水、脑脊液等分离曲菌部分阳性。疑有肺曲菌病时作抗原抗体X线检查。 
治疗方案编辑
1.严格掌握糖皮质激素及广谱抗生素的应用。
2.积极治疗原发病，加强支持疗法，提高机体免疫力。
3.病原治疗
(1)对隐球菌脑膜炎患者：①用二性霉素B加5-氟胞嘧啶联合治疗具有协同作用。二性霉素B lmg/(kg·d)静滴、5-氟胞嘧啶50～150mg/(kg·d)分3次口服或静滴共6周。治疗前、治疗中每2周复查BUN及血象以确定用药的适当时间间隔。治疗前测肾功及血象，对肾功损害及骨髓抑制的患者应慎用(二性霉素B*静脉滴注剂量为0.1mg/(kZ·d)，以后每日增加0.05～0.10mg/kg直至1.0mg/kg，但每日剂量不超过50mg/d，药物溶解于5%葡萄糖液，*浓度为0.1mg/m1)。二性霉素B也可与利福平联合应用，亦有协同作用。②咪康唑(双氯苯咪唑)常用于不能耐受二性霉素B或治疗反应不佳的深部真菌患者。对念珠菌、曲菌、隐球菌、组织胞浆菌或环孢子菌等全身感染有效。剂量：0.6g～1.2g/d分3次静滴，鞘内注射成人20mg每3～7d一次。③氟康唑有广谱抗真菌作用，口服吸收良好，能透过血脑屏障，200mg每日1～2次。④球红霉素口服400～2000U/(kg·d)，静滴40～100U/(kg·d)开始；渐增至600～800U/(kg·d)，成人总量不超过300万～400万U。[3] 
(2)肺部隐球菌病轻型患者可不用抗真菌药物，如无条件随访可口服酮康唑200mg～400mg/d。
4、护理
(1)按传染病一般护理常规护理。高热时按高热护理常规护理。
(2)及时留送痰、血、尿、粪便、脑脊髓液、脓液等，进行常规检查及培养。
(3)3.密切观察病情，特别注意咳嗽、咯血、呼吸、神志改变等，如有变化应及时与医师。
(4)及时做好隔离、空气消毒、口腔卫生、皮肤护理等。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

想了解更多的产品及服务请扫描下方二维码：

【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

【】 
【腾讯  】 
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

Diagnostic test
White blood cell count and classification; repeated fungal smear and culture. Bronchial brush or bronchoalveolar lavage can increase the positive rate. Blood sever is rarely positive. Urine, stools, ascites, cerebrospinal fluid, etc. were partially positive for Aspergillus. Suspected pulmonary aspergillosis for antigen antibody X-ray examination.
Treatment program editor
1. Strict control of glucocorticoid and broad-spectrum antibiotics.
2. Active treatment of the primary disease, strengthen supportive therapy, improve the body immunity.
Pathogen treatment
(1) Cryptococcal meningitis patients: ① amphotericin B plus 5-fluorocytosine combination therapy has a synergistic effect. Amphotericin B lmg / (kg · d) intravenous infusion of 5-fluorocytosine 50 ~ 150mg / (kg · d) were administered orally or intravenously 3 times for 6 weeks. Before treatment, treatment every 2 weeks review of BUN and blood to determine the appropriate time interval of medication. Pretreatment renal function test and blood, renal damage and bone marrow suppression should be used with caution (amphotericin B first intravenous infusion of 0.1mg / (kZ · d), after a daily increase of 0.05 ~ 0.10mg / kg up to 1.0 mg / kg, but the daily dose does not exceed 50mg / d, the drug dissolved in 5% glucose solution, the optimal concentration of 0.1mg / ml). Amphotericin B can also be used in combination with rifampicin, but also synergistic effect. ② miconazole (diclofenac) is commonly used in patients with deep fungi that can not tolerate amphotericin B or respond well to poor reactions. Candida, Aspergillus, Cryptococcus, Histoplasma or Cyclospora and other systemic infections effective. Dosage: 0.6g ~ 1.2g / d intravenous infusion of 3 times, intrathecal injection of adult 20mg once every 3 ~ 7d. ③ fluconazole broad-spectrum antifungal effect, good oral absorption, through the blood-brain barrier, 200mg daily 1 or 2 times. (4) Erythromycin orally 400 ~ 2000U / (kg · d), intravenous drip 40 ~ 100U / (kg · d) began; gradually increased to 600 ~ 800U / (kg · d), the total adult does not exceed 3 million ~ 400 million U. [3]
(2) patients with pulmonary cryptococcosis light anti-fungal drugs may not, such as unconditional follow-up may be taken ketoconazole 200mg ~ 400mg / d.
4, nursing
(1) According to the general nursing care routine care. High fever by high heat care routine care.
(2) promptly leave phlegm, blood, urine, stool, cerebrospinal fluid, pus, etc., for routine examination and training.
(3) 3. Closely observe the condition, with particular attention to cough, hemoptysis, breathing, mind changes, etc., if any changes should be promptly linked with the physician.
(4) timely isolation, air disinfection, oral hygiene, skin care and so on.