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當前位置：深圳欣博盛生物科技有限公司>>特色試劑盒>> PGE2 high sensitivity ELISA kit
Progranulin (mouse) ELISA Kit試劑盒
VECTASTAIN® Elite ABC-HRP Kit,
QuantiCyto® Mouse IL-12p70 ELI
| 供貨周期 | 兩周 | 規(guī)格 | 1*96wells |
|---|---|---|---|
| 貨號 | ADI-930-001 | 應用領域 | 生物產業(yè) |
| 主要用途 | 科研 |
Ultrasensitive measurement, detecting as little as 8.26 pg/ml PGE2
Validated in a wide variety of sample matrices
Reliable and reproducible results lot-after-lot and day-after-day
Fully quantitative results that surpass semi-quantitative Western blot analysis
| Alternative Name: | Prostaglandin E2 |
| Sensitivity: | 8.26 pg/ml (range 7.8 - 1,000 pg/ml) |
| Assay Time: | Overnight + 1 hour |
| Applications: | ELISA, Colorimetric detection |
| Application Notes: | For the quantitative determination of PGE2 in culture supernatants, serum, saliva, urine, and whole blood from any species. Cited sample types include plasma. |
| Wavelength: | 405 nm |
| Species reactivity: | Species independent |
| Use/Stability: | Store all components at +4°C, except standard and conjugate at -20°C. |
| Shipping: | Shipped on Blue Ice |
| Contents: | GxM IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
| Scientific Background: | Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and sepsis. Oxidation of arachidonic acid by prostaglandin synthases (COX-1 and COX-2) produces prostaglandin H2 (PGH2), which is further metabolized by PGE synthases into its major product, PGE2. PGE2 mediates autocrine and paracrine signaling by binding to G-protein coupled receptors (EP1, EP2, EP3, EP4) on the cell surface, functioning to modulate phospholipase C and adenylate cyclase activity. PGE2 has been of great interest as a therapeutic target, either by modulation of its synthesis by COX inhibitors (NSAIDS) or by modulation of its receptors by downregulation or binding antagonists. PGE2 production in a variety of tissues has been shown to modulate numerous physiological processes including natriuresis in the kidney, smooth muscle elasticity in the vasculature, and the inflammatory response to damaged tissues by monocytes and macrophages. |
| Regulatory Status: | RUO - Research Use Only |
| Compatibility: | This product is compatible with the Absorbance 96 Plate Reader. |
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