HVEM/U2OS Cell HVEM/U2OS Cell HVEM/U2OS Cell
| I. Background | |
疱疹病毒进入介质（HVEM），也称为肿瘤坏死因子受体超家族成员 14 （TNFRSF14），是 TNF 受体（肿瘤坏死因子）超家族的人细胞表面受体。HVEM 在多种 免疫细胞中表达，包括 T 细胞、B 细胞、自然杀伤细胞、树突状细胞和内皮细胞。它还通 过在黑色素瘤细胞上的频繁表达参与肿瘤的免疫逃避。 | |
| II. Introduction | |
| Expressed gene: | HVEM |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | Mccoy's5A+10%FBS+2 μg/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
Figure 1. Recombinant HVEM/U2OS Cell constitutively expressing HVEM. | |
Figure 2. Inhibtion of HVEM Induced SHP2 Recruitment In BTLA SHP2 Reporter Cell (C11) By Icatolimab with HVEM U2OS Cell (C7). | |
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