| CBP73258 | |
| I. Introduction | |
Cell Line Name： | ERBB4 E452K (NRG1b Dependent)/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+10ng/ml NRG1-beta1 |
Mycoplasma Status: | Negative |
| II.Background | |
Human HER4 kinase, also known as Erb-B4, Proto-Oncogene-Like Protein C-ErbB-4, and Tyrosine Kinase-Type Cell Surface Receptor HER4, GenBank Accession No. NM_005235, a.a. 708-993, with an N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=59.5 kDa. | |
| III. Representative Data | |
1.ERBB4 E452K (NRG1b Dependent)/BaF3
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2. Anti-proliferation assay
Figure 2. Anti-proliferation assay of two reference compounds on the ERBB4 E452K (NRG1b Dependent)/BaF3 Stable Cell line. | |
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