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C6830Interferes with Cell Membrane

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上海辅泽商贸有限公司
2018-08-20 10:13:41
上海市
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【简单介绍】

品牌	Sigma-Aldrich	货号	C6830
规格	Cecropin A ≥97% (HPLC), powder	供货周期	一周

Interferes with Cell Membrane Permeability （Ionophores）

【详细说明】

Interferes with Cell Membrane Permeability (Ionophores)

Polymyxin B and colistin (polymyxin E) disrupt the cell membrane integrity of Gram-negative bacteria by binding to membrane phospholipids. Eukaryotic cell membranes have phospholipids similar to Gram-negative bacteria, so the polymyxins are most often used clinically as topical antibiotics.

In contrast, the ionophore antibiotics such as monensin and valinomycin tend to be more active against Gram-positive bacteria, which lack the outer cell membranes. Monensin is an ionophore that forms monovalent ion channels in the cell wall of Gram-positive bacteria and allows the free movement of K+ and Na+ ions along their concentration gradients. Valinomycin is a selective K+ ionophore that triggers mitochondrial transition by facilitating the transport of K+ across the mitochondrial membrane. By altering the intracellular cationic environment of the cell, these agents uncouple mitochondrial oxidative metabolism and inhibit cell growth.

Product #	Description	Add to Cart
100105	A mobile ion-carrier that forms stable complexes with divalent cations.	价格

407950	Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is an ionophore with high specificity for divalent cations. More effective than A23187 as a mobile ion carrier for Ca2+., Ionomycin, Free Acid, Streptomyces conglobatus, CAS 56092-81-0, is a highly specific for divalent cations and more effective than A23187 as a mobile ion carrier for Ca²⁺.	价格

407951	null	价格

407952	Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.	价格

407953	Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is a 10 mM solution in DMSO. Useful in cell activation experiments when calcium dose-response data are not required., Useful in cell activation experiments when calcium dose-response data are not required. The solid form of this compound is also available.	价格

475914	Nystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+., A polyene antifungal antibiotic effective against yeast and mycoplasma.	价格

481990	Nigericin, Sodium Salt, Streptomyces hygroscopicus, CAS 28643-80-3, is an antibiotic K+ ionophore that disrupts the membrane potential and stimulates ATPase activity in mitochondria., Disrupts the membrane potential and stimulates ATPase activity in mitochondria.	价格

SRP3013	Beta D-4 human recombinant, expressed in E. coli, ≥98% (HPLC), cell culture tested	价格

SRP3012	Beta D-1 (47 aa) human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested	价格

C6830	Cecropin A ≥97% (HPLC), powder	价格

C1796	Cecropin B ≥97% (HPLC), powder	价格

C7927	Cecropin P1 Porcine ≥95% (HPLC), powder	价格

C4461	Colistin sulfate salt 硫酸盐 ≥15,000 U/mg	价格

D2043	Defensin HNP-1 human ≥80% (HPLC)	价格

D6790	Defensin HNP-2 human ≥95% (HPLC)	价格

E4632	Econazole nitrate salt	价格

M7402	Magainin II ≥97% (HPLC)	价格

SRP3126	NP-1 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested	价格

P0053	PGLa	价格

03907	Tioconazole 97%	价格

C6019	克霉唑	价格

33894	克霉唑 VETRANAL^™, analytical standard	价格

P4668	吡喹酮 anthelminic, neurogenic	价格

46648	吡喹酮 VETRANAL^™, analytical standard	价格

P9625	吩嗪硫酸甲酯 ≥90% (UV)	价格

P1004	多粘菌素 B 硫酸盐	价格

H3261	2-巯基吡啶-N-氧化物钠盐 ≥96%	价格

A3281	N-(6-氨基己基)-5-氯-1-萘磺酰胺盐酸盐	价格

C6143	氯己定二乙酸盐水合物 bis(biguanide) antimicrobial	价格

C9394	氯己定二葡糖酸盐溶液 20% in H₂O	价格

C9275	钙离子载体 A23187 半钙盐 powder	价格

21186	钙离子载体 III Selectophore^™, function tested	价格


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C6830Interferes with Cell Membrane

Interferes with Cell Membrane Permeability (Ionophores)

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