| 英文名称 | Anti-LIFR Polyclonal Antibody |
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| 宿主 | Rabbit |
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| 别名 | CD118;LIF-R;SJS2;STWS;SWS |
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| 应用 | WB |
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| 稀释比例 | WB 1:500-2000. |
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| 交叉反应 | Human |
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| 蛋白分子量 | 115kDa |
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| Gene ID | 3977 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
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| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | A synthetic peptide of human LIFR |
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| 性状 | 液体 |
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| Public Immunogen Range | A synthetic peptide of human LIFR |
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| Subcellular Locations | Cytoplasm Cell membrane |
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| Swiss Prot | P42702 |
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| 克隆类型 | Polyclonal Antibody |
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| 背景资料 | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |
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