| 英文名称 | Anti-TLR4 Polyclonal Antibody |
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| 宿主 | Rabbit |
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| 别名 | ARMD10;CD284;TLR-4;TOLL |
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| 应用 | WB |
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| 稀释比例 | WB 1:500-2000. |
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| 交叉反应 | Human Mouse Rat |
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| 蛋白分子量 | 73kDa |
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| Gene ID | 7099 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
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| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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| 纯化方法 | Affinity purification |
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| 亚型 | IgG |
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| 免疫原 | Recombinant protein of human TLR4 |
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| 性状 | 液体 |
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| Public Immunogen Range | Recombinant protein of human TLR4 |
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| Subcellular Locations | Cytoplasm Cell membrane |
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| Swiss Prot | O00206 |
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| 克隆类型 | Polyclonal Antibody |
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| 背景资料 | Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. |
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