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C3G (phospho Tyr504) rabbit pAb
- 公司名稱 上海貝博生物科技有限公司
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- 更新時間 2025/7/15 15:04:33
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Source
Rabbit
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Applications
WB,IHC,ELISA
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Reactivity
Human
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Dilution
WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
Phospho-C3G (Y504) Polyclonal Antibody detects endogenous levels of C3G protein only when phosphorylated at Y504.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519
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Uniprot No
Q13905
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Alternative names
RAPGEF1; GRF2; Rap guanine nucleotide exchange factor 1; CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3G
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
Rap guanine nucleotide exchange factor 1(RAPGEF1) Homo sapiens This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
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Other
RAPGEF1, Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing factor 2; Protein C3G
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Mol.Wt (Da)
120548
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Concentration
1 mg/ml
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