AR雄激素受体（鼠单克隆抗体）

广州健仑生物科技有限公司

雄激素中zui主要的形式为睾酮，雄激素在体内起着重要的作用。除了与生植相关外，还具有保持体内激素平衡；刺激蛋白质合成代谢，促进氮沉积和增加肌纤维的数量和厚度等。通过对青春期前的猪（体重约为15kg）和青春期的猪（体重约为74kg）分组试验，结果表明公猪的饲料报酬率比去势公猪高20%，用睾酮或二氢睾酮处理的去势公猪，蛋白质合成率显着高于对照去势公猪，蛋白质降解率显着低于对照去势公猪（Mulvaney，1984）。James T等（1992）通过用去甲雄三烯醇酮乙酸盐处理小公牛，结果发现经处理的小公牛平均日增重高于对照小公牛（P<O.001）。Tarocco C等（1986）对63头大白公猪从30到130kg活重进行表型检测发现血液中睾酮浓度与背膘呈显着相关。然而雄激素是通过与雄激素受体（Androgen Receptor-AR）结合而发挥其功能的，若无雄激素受体，则雄激素对组织无刺激反应（refractory）。雄激素受体是雄激素作用的中介物质。许多年来欧美一些国家一直在研究雄激素受体基因。

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【产品介绍】

细胞定位：细胞核

克隆号：AR441

同型：IgG1

适用组织：石蜡/冰冻

阳性对照：前列腺

抗原修复：热修复（EDTA）

抗体孵育时间：60min

AR雄激素受体（鼠单克隆抗体）

3.并发症的治疗
在积极有效的灭滴灵或抗原抗体治疗下，肠道并发症可得到缓解。暴发型患者有细菌混合感染，应加用抗生素。大量肠出血可输血。肠穿孔、腹膜炎等必须手术治疗者，应在灭滴灵和抗生素治疗下进行。
肠阿米巴病若及时治疗预后良好。如并发肠出血、肠穿孔和弥漫性腹膜炎以及有肝、肺、脑部转移性脓肿者，则预后较差。治疗后粪检原虫应持续6个月左右，以便及早发现可能的复发。
4.诊断性治疗
如临床上高度怀疑而经上述检查仍不能确诊时，可给予足量抗原抗体注射或口服安痢平、灭滴灵等治疗，如效果明显，亦可初步作出诊断。
预防
治疗患者及携带包囊者，饮水须煮沸，不吃生菜，防止饮食被污染。防止苍蝇孳生和灭蝇。检查和治疗从事饮食业的排包囊及慢性患者，平时注意饭前便后洗手等个人卫生。
环瓜氨酸肽（cyclic citrullinated peptide，CCP）
瓜氨酸是类风湿病患者血清中抗丝聚蛋白相关抗体识别的主要组成性抗原决定簇成分。采用CCP为抗原基质检测类风湿患者血清中的抗CCP抗体， 具有较高的敏感性和*的特异性。有研究提示抗CCP参与了类风湿发病过程。除此之外，抗CCP抗体阳性的类患者更容易出现关节的骨质损坏。因此，抗CCP抗体阳性者的愈后可能较差，应采取更积极的治疗措施。
抗环瓜氨酸肽抗体是风湿自身抗体系统的一种，类风湿关节炎（RA）具有高特异性的瓜氨酸相关自身抗体系统包括AKA、APF、AFA、抗CCP抗体，这些抗体对早期RA诊断具有较好的特异性。这些指标越高患风湿的可能性也越大。
抗环瓜氨酸肽抗体（CCP）是环状聚丝蛋白的多肽片段，是以IgG型为主的抗体，对类风湿性关节炎（RA）具有很好的敏感性和特异性，且抗CCP抗体阳性的RA病人骨破坏较抗CCP抗体阴性者严重。
类风湿性关节炎（rheumatoid arthritis,RA）是一种常见的慢性自身免疫性疾病。在*大约有1%的人罹患此病。RA能引起关节的疼痛、僵直及肿胀。在发病2年内即可能出现不可逆的骨关节损伤，并可引起多种并发症，如神经系统疾病、心包炎、淋巴腺炎等。因此，及早诊断RA及给予缓解病情的药物治疗，对控制病情非常重要。1998年，国外，*报道的抗环瓜氨酸肽抗体（anti-cyclic cirullinated peptide antibodies,抗CCP抗体）的检测，对RA具有较高的敏感性和特异性，是RA新的血清标志物。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【腾讯  】 
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

3. Complications of treatment
In the active and effective metronidazole or antigen antibody treatment, intestinal complications can be eased. Outbreaks of patients with bacterial infection, antibiotics should be added. A large number of intestinal bleeding can be transfused. Intestinal perforation, peritonitis and other surgery must be treated with metronidazole and antibiotics.
If the timely treatment of intestinal amoebas disease prognosis is good. Such as intestinal bleeding, intestinal perforation and diffuse peritonitis and liver, lung, brain metastatic abscess, the prognosis is poor. After treatment stool protozoa should last about 6 months, in order to detect possible early detection of recurrence.
4. Diagnostic treatment
If the clinical suspicion is high and can not be confirmed by the above examination, sufficient antigen or antibody can be given or oral An Li Ping, metronidazole and other treatment, such as the effect is obvious, but also make a preliminary diagnosis.
prevention
Treatment of patients and patients with cysts, drinking water to be boiled, do not eat lettuce, to prevent food contamination. Prevent flies from breeding and flies. Inspection and treatment of the catering industry in the cysts and chronic patients, usually pay attention to personal hygiene before and after washing hands and so on.
Cyclic citrullinated peptide (CCP)
Citrulline is a major constitutive antigenic determinant recognized by anti-fibrin-related antibodies in the serum of rheumatoid patients. Using CCP as the antigen matrix to detect anti-CCP antibody in the serum of rheumatoid patients has high sensitivity and high specificity. Some studies suggest that anti-CCP is involved in the pathogenesis of rheumatoid arthritis. In addition, anti-CCP antibody-positive patients are more prone to joint bone damage. Therefore, anti-CCP antibody-positive patients may be worse after healing, should take more aggressive treatment.
Anti-cyclic citrullinated peptide antibody is a rheumatoid autoantibody system that has high specificity for rheumatoid arthritis (RA). Citrulline-related autoantibody systems include AKA, APF, AFA, anti-CCP, RA diagnosis has good specificity. The higher these indicators, the greater the risk of rheumatism.
Anti-cyclic citrullinated peptide antibody (CCP) is a polypeptide fragment of cyclic fibroin, which is an IgG-based antibody with good sensitivity and specificity for rheumatoid arthritis (RA) Anti-CCP positive RA patients with bone destruction than anti-CCP antibody negative were serious.
Rheumatoid arthritis (RA) is a common chronic autoimmune disease. About 1% of people in the world suffer from the disease. RA can cause joint pain, stiffness and swelling. Irreversible bone and joint damage may occur within 2 years of onset and may cause various complications such as nervous system diseases, pericarditis and lymphadenitis. Therefore, early diagnosis of RA and given to alleviate the condition of the drug treatment, the control of the disease is very important. In 1998, foreign countries, the first reported anti-cyclic citrullinated peptide antibodies (anti-CCP antibody) detection, RA has high sensitivity and specificity, is a new serum marker of RA.