(S,S,S)-AHPC hydrochlorid MCE | (S,S,S)-VH032-NH2 hydrochloride
- 公司名称 MedChemExpress LLC
- 品牌 MedChemExpress (MCE)
- 型号 (S,S,S)-AHPC hydrochlorid
- 产地 美国
- 厂商性质 生产厂家
- 更新时间 2021/7/28 9:42:02
- 访问次数 572
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CAS | 2115897-23-7 | 分子量 | 467.02 |
---|---|---|---|
分子式 | C??H??ClN?O?S | 供货周期 | 现货 |
规格 | 电询 | 货号 | HY-125845A |
应用领域 | 生物产业 | 主要用途 | 科研 |
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(S,S,S)-AHPC hydrochloride
产品活性:(S,S,S)-AHPC hydrochloride 是一种 von Hippel-Lindau (VHL) 氨基砌块。(S,S,S)-AHPC (Compound 27) 常作为 (S,R,S)-AHPC 的阴性对照。(S,R,S)-AHPC 是一种基于 VH032 的,可募集 VHL 蛋白的 VHL 配体。
研究领域:PROTAC
作用靶点:Ligand for E3 Ligase
In Vitro: The VHL protein is a substrate recognition subunit of two ubiquitously expressed and biologically important Cullin RING E3 ubiquitin ligase complexes. VHL is one of the most popular E3 ligases being recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein.
相关产品:Bioactive Compound Library Plus | Anti-Cancer Compound Library | Ubiquitination Compound Library | Lenalidomide | Pomalidomide | Thalidomide | VH-298 | (S,R,S)-AHPC hydrochloride | Thalidomide-O-COOH | Thalidomide-5-OH | VL285 | Thalidomide 4-fluoride | VH032 | Thalidomide-O-C8-COOH | Thalidomide-propargyl | VH032-cyclopropane-F | (S,R,S)-AHPC-propargyl | E3 ligase Ligand 8 | Lenalidomide-OH | KB02-COOH | Thalidomide-O-C8-Boc | (4R,5S)-Nutlin carboxylic acid | E3 ligase Ligand 9 | NV03 | Thalidomide-NH-PEG3-CH2CHO | β-Naphthoflavone-CH2-Br | β-Naphthoflavone-CH2-OH






